This Technical Note presents a comprehensive framework of ten evidence-based principles for improving decision-making effectiveness in leadership contexts. Drawing from cognitive science, behavioral economics and management theory, it addresses the critical challenge that leaders face in making sound decisions under pressure and uncertainty.The ten principles cover: understanding and avoiding cognitive biases, recognizing the importance of decision framing, embracing probabilistic thinking, structuring information effectively, encouraging constructive disagreement, leveraging diverse perspectives, fostering inclusive decision making, implementing structured decision rules, balancing deliberation with speed, and intelligently integrating analytics. Each principle is supported by practical tools and techniques, from emotional regulation training to weighted decision matrices.The note emphasizes how cognitive biases become more pronounced under stress and pressurecommon conditions in leadership roles. It provides specific strategies for activating deliberate, analytical thinking System 2 over fast, intuitive responses System 1 when making important decisions. The framework integrates insights from leading researchers such as Daniel Kahneman, Annie Duke and Amy Edmondson.This comprehensive guide serves as both a theoretical foundation and practical toolkit for leaders seeking to improve their decision-making capabilities. It acknowledges the reality that leaders must often make decisions quickly while maintaining quality, providing frameworks that support both speed and accuracy in complex business environments.